Collagen Structure-Function Mapping Informs Applications for Regenerative Medicine
نویسندگان
چکیده
منابع مشابه
Collagen: Applications of a Natural Polymer in Regenerative Medicine
Collagen is a naturally occurring matrix polymer which is highly conserved across species. It is the predominant extra-cellular matrix component of most connective tissues within the mammalian body, comprising one third of all protein found within tissues. Collagens are extracellular and have a mainly structural role. Critical parameters including density, packing and orientation (or direction)...
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The basic building block of the extra-cellular matrix in native tissue is collagen. As a structural protein, collagen has an inherent biocompatibility making it an ideal material for regenerative medicine. Cellular response, mediated by integrins, is dictated by the structure and chemistry of the collagen fibers. Fiber formation, via fibrillogenesis, can be controlled in vitro by several factor...
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1 Department of Cariology, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki 852-8588, Japan 2Department of Oral Biology, NC Oral Health Institute, University of North Carolina, Chapel Hill, NC 27599-7455, USA 3Department of Chemistry, Marine Bioprocess Research Center, Pukyong National University, Busan 608-737, Republic of Korea 4Department of Environmental and Biological C...
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ژورنال
عنوان ژورنال: Bioengineering
سال: 2020
ISSN: 2306-5354
DOI: 10.3390/bioengineering8010003